It has been used in the adjuvant setting to manage postoperative recurrent hepatic tumors.
All five individuals were reported to be alive and well 24 months after diagnosis, and none developed a recurrent tumor during follow-up.
Importantly, 43% to 50% of these recurrent tumors will be malignant and require adjuvant chemotherapy.
Most children with recurrent sacrococcygeal tumors will recur locally at the primary tumor site.
Thus it was clear that the clonality was different between primary and recurrent tumours.
Usually, recurrent tumors after radiation are treated with surgery, and not with radiation.
The time it takes for a recurrent tumor to be visible to the patient might be 5 or more years.
Of all treatment methods available, Mohs micrographic surgery has the highest 5-year cure rate for both primary and recurrent tumors.
Some responses were durable but progression was common, usually at the site of the previously recurrent tumor.
However, six months later, an MRI showed a recurrent tumor.