This was getting to be a real pain and fast.
Some people find reading and writing more of a challenge than others which can make school work a real pain.
There was a real, physical pain where her heart lived.
"The fact that I have to go to school every day is a real pain," he said.
That guy over there can be a real pain sometimes, too.
"I have already told you there is no such thing as real pain."
It seems to me that would be a real pain.
He hadn't, actually, expected to see real pain in her eyes.
It can be a real pain making sure you have the right insurance on all of them.
For her, this was only the beginning of the real pain.