Also, the rate-limiting steps for one substance may be in common with other substances.

Attack by aspartate is the rate-limiting step of the reaction.

In the S1 reaction, the nucleophile attacks after the rate-limiting step is over.

The initial nucleophilic attack on the azide is the rate-limiting step.

It is the initial and rate-limiting step in pyrimidine catabolism.

However, excretion is the rate-limiting step, and usually impaired to the greatest extent.

Hammond's postulate is especially important when looking at the rate-limiting step of a reaction.

In this case one must examine the rate-limiting step and the intermediates.

Often, the rate-limiting step is the initial formation of an unstable species such as a carbocation.

The E1-catalyzed process is the rate-limiting step of the whole pyruvate dehydrogenase complex.