In laboratory experiments, Dr. Stevens treated slices of rat hippocampus with an inhibitor of carbon monoxide formation.
A recent study reported a high degree of variation in RNA levels in rat hippocampus taken from different animals.
It has been found to stimulate the expression of NGF and BDNF in rat hippocampus.
Local application of estrogen in the rat hippocampus has been shown to inhibit the re-uptake of serotonin.
Based on this discovery, O'Keefe and Nadel hypothesized that the primary function of the rat hippocampus is to form a cognitive map of the rat's environment.
While working on rat hippocampus, Sohail Qureshi identified over fifty novel genes and studied the function(s) of two novel transcription factors in great detail.
Experimentally when substance P is injected into the rat hippocampus, it significantly lowers the initiation threshold for seizures induced in a dose-dependent manner.
Many studies currently examine the memory system of rats, particularly the rat hippocampus, dealing with place cells, which fire for a specific location that has been learned.
Acute administration of ketamine at the higher dose, but not imipramine, increased BDNF protein levels in the rat hippocampus.