The usefulness for individuals or their doctors of testing for the protein variant is unclear.

Acceleration of the in vitro folding rate in mutant protein variants with one or more proline residues replaced by another amino acid.

The locus is alternatively spliced and predicted to yield five protein variants, three of which contain a protein domain of unknown function, DUF1741.

The largest protein variant is 689 amino acids in length.

Also, a mitochondrial sorting signal was identified at the beginning of one of the protein isoforms using MitoProt II (located at Met416 of the largest protein variant).

These variants can then be ligated into an expression vector, individual clones can be created, and the encoded protein variants can be expressed.

Hence detection of this protein variant in blood could be used as a biomarker for early detection of lung cancer.

There are 26 non-synonymous variants of A*03, 4 nulls, and 22 protein variants.

That is partly because there are more proteins than genes, since a single gene can make more than one protein variant and because proteins can change shape as they act.

Variant 1 is the longest and most common protein coding variant.