As this protein accumulates it causes the cells to malfunction, and the animal presents with clinical signs of "madness".
In all cases, the mutant proteins accumulate within neurons and are not cleared properly.
This protein accumulates throughout the differentiation, ensuring the survival of erythroid progenitors.
The excessive protein accumulates throughout the body, causing organ damage.
In these cells the region for hair initiation overlaps, but is only a small part of the region where these proteins accumulate.
Amyloidosis is a condition where degraded proteins accumulate in body tissues.
With them, the misfolded proteins accumulate inside the cell, interact with things they shouldn't and send off the wrong chemical signals.
As more misfolded proteins accumulate, they kill nerve cells.
The result is that misfolded proteins accumulate into gunk that can be benign or toxic.
Without ADA, certain proteins accumulate that harm white blood cells.