Patients with accelerated silicosis are at greater risk for complicated disease, including progressive massive fibrosis (PMF).
Coal worker's pneumoconiosis occurs in two forms: simple and complicated (also called progressive massive fibrosis, or PMF).
The primary pathologic change seen in atrial fibrillation is the progressive fibrosis of the atria.
Dr. Olivieri's data suggested that deferiprone leads to progressive hepatic fibrosis.
Her data, which suggested that deferiprone led to progressive hepatic fibrosis, are also disputed.
Rapidly progressive interstitial renal fibrosis associated with Chinese herbal medications.
This causes atrophy of the exocrine glands and progressive fibrosis.
Early recognition and treatment with the antifilarial drug, diethylcarbamazine, is important, as delay before treatment may lead to progressive interstitial fibrosis and irreversible impairment.
Caplan syndrome was originally described in coal miners with progressive massive fibrosis.
Overall, about 50% develop permanent pulmonary abnormalities, and 5 to 15% have progressive fibrosis of the lung parenchyma.