Like the populists, the pious Protestants were profoundly opposed to Irish nationalism and republicanism and hence tended to be aggressive in defence of the Union with Britain.
She wrote in a letter to The New York Times in 1976, "I am profoundly opposed to Ronald Reagan.
Although keen to attract industry into funding health science, he is profoundly opposed to companies setting up 'slush funds' that would cover the costs of a particular project.
Oppenheimer's view of the state is profoundly opposed to the then dominant characterisation propounded by G. W. F. Hegel of the state as an admirable achievement of modern civilisation.
It's hard to reckon, for one, how a man and a woman with such profoundly opposed viewpoints on matters of life and death could live in harmony for so many years.
Both Smiths, however, were profoundly opposed to a number of practices, especially plural marriage, and refused to join the Utah church.
Because the raven and coyote reconcile profoundly opposed concepts (i.e., life and death), their own mythical personalities must reflect this duality or contradiction: in other words, they must have a contradictory, "tricky" personality.
Sofer was profoundly opposed to the reformers and attacked them in his speeches and writings.
Throughout his life he was profoundly opposed to all forms of socialism and fascism.
President Bush arrived in office so profoundly opposed to peacekeeping that he scarcely bothered with post-conflict planning in Iraq.