In such small and large ways they have profoundly influenced a region, a society.
She did not understand its meaning at the time, but it would profoundly influence her later life.
All three had been profoundly influenced by the magazine in earlier years.
"America doesn't allow itself to be influenced profoundly by outside culture," he said.
She died when he was nine months old, profoundly influencing his life.
He was profoundly influenced by his early years in Rome.
The makeup and role of the board were profoundly influenced by two events in the late 1970's.
They have the capacity to form public opinion and to profoundly influence important decisions.
The forest thus profoundly influences all the action of the novel.
But seldom does the choice profoundly influence the outcome of the campaign.