Clearly the whole imperialist aim of theoretical science to be the royal and single road to knowledge has been a profound mistake.

President Bush made one profound mistake immediately after Iraq conquered Kuwait.

Mora evaluated the work being prepared by the Working Group as containing "profound mistakes in its legal analysis" and as "unacceptable".

He criticized the negotiations and indicated that the missile pact would be a profound mistake unless linked to relieving the Soviet advantage in conventional arms.

If the Kremlin thought that an act of such ruthlessness would weaken British will, it was making a profound mistake, one which had been made before.

Although he is now moving on with his own life, I live with constant anguish that my profound mistake cost him so dearly.

If it does not know the word, it makes a guess, resulting in hilarious and occasionally profound mistakes.

It would be a profound mistake for the secularists to burn their bridges with the MB at this stage.

"Any request like this prior to Nov. 7 would, I think, be a significant, profound and historical mistake of the United States."

That would be a profound mistake.