With that fearful notion came a profound fatigue, rolling irresistibly over him like the fogs of Argelius II.

Sorrow and profound fatigue are at the heart of Dewey's silence.

His ancient mental voice betrayed a profound fatigue.

"Yourrr parrrdon," Hydona said, as she read the signs of bone-deep, profound fatigue that the woman's control had hidden with fair success.

Her profound fatigue, her moaning in the night and her husband's philandering are all darkly linked to Bill's increasingly promiscuous behavior.

In the meantime, patients frequently lose weight and suffer the effects of dehydration, including profound fatigue.

Some CFS sufferers will experience profound fatigue even after very modest exercise, so start off slowly.

Cisplatin, for example, often produces terrible nausea and profound fatigue, as well as transient hair loss.

Once they were airborne, Lara's stress evolved into profound fatigue.

The ongoing hypoxia, coupled with my profound fatigue, exacerbated the sense of chaos and despair.