The World Health Organization (2003) has labeled poor adherence to prescription medications and treatment a "worldwide problem of striking magnitude".
Industry representatives, administrators and doctors say that much of the fault for poor adherence lies with the regulators themselves.
They are manufactured both as metallized and as film/foil types, although poor adherence to the film makes metallization difficult.
CHD costs the NHS in excess of £2billion on medicines; 50% of which is wasted through poor understanding and poor adherence.
This poor adherence results in significant increase in illness, disability, symptoms and even death.
Donnell stated that Moosally's "poor adherence to explosive safety regulations and ordnance safety" and "his failure of leadership" were a "marked departure from an otherwise outstanding performance".
No adverse effects have been reported with the use of oral nystatin for treatment of oral candidiasis, but bitter taste might contribute to poor adherence.
Because classical rail has poor adherence, Cordier designed a raceway made of two granite rails embedded in concrete with a continuous guide rail between them.
Often this was facilitated by the lack of proper axes and poor adherence to basic rules of graph construction and design.
"One of the definite predictors of poor adherence to treatment is the complexity of the regimen."