Beta-Thromboglobulin also affects megakaryocyte maturation, and thus helps in regulating platelet production.
Smoking also raises the levels of fibrinogen and increases platelet production (both involved in blood clotting) which makes the blood viscous.
Patients with p. vera and essential thrombocythemia have marked increases of red blood cell and platelet production, respectively.
It can be associated with chemotherapy, radiation therapy, myelofibrosis and aplastic anemia (failure of white cell, red cell & platelet production).
Bone marrow biopsy from Harrington's sternum demonstrated normal megakaryocytes, the cells necessary for platelet production.
This information may identify ineffective platelet production as the cause of thrombocytopenia and rule out a malignant disease process at the same time.
Corticosteroids may be used to increase platelet production.
Thrombopoietin receptor agonists are pharmaceutical agents that stimulate platelet production in the bone marrow.
Their platelet production increased by 400 percent.
Megakaryocytopoiesis is the cellular development process that leads to platelet production.