In pharmacological doses niacin has been proven to reduce total cholesterol, triglyceride, very-low-density lipoprotein, low-density lipoprotein, and increase high-density lipoprotein levels (Kamanna et al., 2008).

Patients whose POTS symptoms are due to B12 deficiency need pharmacological doses of B12 for repletion of tissues.

Based on solid evidence, high-intensity smokers who take pharmacological doses of beta carotene have an increased lung cancer incidence and mortality that is associated with taking the supplement.

Reduction of blood pressure is also observed when pharmacological doses are applied.

Ascorbic acid has been used in pharmacological doses for more than 20 years.

In vivo , fentanyl is a strong analgesic agent in pharmacological doses due to its interaction with μ opioid receptors [ 19 ] .

Effect of pharmacological daytime doses of melatonin on human mood and performance.

"And when a patient is given a pharmacological dose of succinylcholine, he can't breathe."

In the 1970s, therapy with pharmacological doses of glucocorticoids was widely used in patients with sepsis and septic shock.

However, later in the mid-1980s, pharmacological doses of glucocorticoids for the treatment of sepsis were investigated extensively until several clinical trials gave negative results [ 10, 11, 12].