In 1955 he led a team of Cambridge chemists who reported the solution of what was one of nature's most perplexing puzzles: the exact chemical structure of vitamin B-12.

Solve perplexing puzzles, locate important items, and enjoy fun mini-games.

For the Mensa applicant, this is a perplexing puzzle.

Well it would be if it wasn't for the tricky traps, perplexing puzzles, tantalising time limit and crafty creatures with an appetite for raw Rufus!

As with all Dizzy games,Crystal Kingdom is jam-packed with perplexing puzzles to solve.

Not least, it resolves the perplexing puzzle of what went on 'before' the Universe began, and what will happen 'after' it has ended.

And, the most perplexing puzzle of all, just what is the phenomenal nature of the kingfisher's experience as it gazes into the water?

C1 Gene's link to cancer is still a perplexing puzzle.

It was a perplexing puzzle, and occupied him a long time; but he ended, finally, with the conviction that she did know him, and had repudiated him for interested reasons.

In recent days, the dredges had brought up arm rests from seats, small engine parts, and other pieces of metal that might eventually fill some gap in the perplexing puzzle.