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Common examples used to show degrees of penetrance are often highly penetrant.
'You, however, have been a complete enigma to our most penetrant minds.
Time and space have yielded not an iota of their mystery to our most penetrant minds.
Time praised the imagery and 'penetrant thought', but judged the novel the weakest of the series to date.
Kathryn flared, and again her most penetrant probe of force flattened out against the Arisian's screen.
"The Eddorians have succeeded finally in inventing a mechanical generator able to block our most penetrant thoughts.
Untreated, this is a completely penetrant genetic disorder causing brain damage and progressive mental retardation.
They felt a creeping chill that was more insidious, more penetrant than the iciness of the unseen walls.
Penetrant testing.
If an allele is highly penetrant, then the trait it produces will almost always be apparent in an individual carrying the allele.
Families are defined as having HP, if the phenotype is consistent with highly penetrant autosomal dominant inheritance.
The mutant phenotypes were largely penetrant with all cells from a mutant strain responding identically.
However, such germline mutations (which cause highly penetrant cancer syndromes) are the cause of only about 1 percent of cancers.
Although such cancer susceptibility genes are very important, highly penetrant germline mutations are estimated to account for only 5% to 10% of breast cancers overall.
Excess Penetrant Removal:
However his advertising of the game quickly reached penetrant levels where he would only talk about the game and try to convince others to play it at every occasion.
The captive was standing utterly rigid, eyes closed, every sense and faculty mustered to resist that cruelly penetrant attack upon the innermost recesses of his mind.
In more severe cases of type 1 vWD, genetic changes are common within the vWF gene and are highly penetrant.
Highly penetrant alleles, and highly heritable symptoms, are easier to demonstrate, because if the allele is present, the phenotype is generally expressed.
For highly penetrant Mendelian genetic disorders such as Huntington's disease virtually all the incidence of the disease is due to genetic differences.
Although fully penetrant, since the syndrome has variable expressivity, one generation may have a mild expression of the syndrome, while the next may be profoundly affected.
The pedigrees demonstrated FASPD to be a highly penetrant, autosomal dominant trait.
It is now generally accepted that FAP is fully penetrant (polyps are present) if the bowel is examined endoscopically.
Teeth that are present at birth (natal teeth) are a specific feature of PC-2 but they are not always present (not fully penetrant).
Much of it has the character of informal jottings, random but penetrant reflections on art and life; there are also droll anecdotes and lacerating, confessional self-criticism.