Although unusual, the following paradoxical reactions have been shown to occur:

A paradoxical reaction or paradoxical effect is an effect of medical treatment, usually a drug, opposite to the effect which would normally be expected.

An example of a paradoxical reaction is when a pain relief medication causes an increase in pain.

This can be regarded as a paradoxical reaction.

Caution is required when benzodiazepines are used in people with personality disorders or mental retardation because of frequent paradoxical reactions.

There are also serious paradoxical reactions that may occur in conjunction with the use of sedatives that lead to unexpected results in some individuals.

In susceptible individuals, midazolam has been known to cause a paradoxical reaction, a well-documented complication with benzodiazapines.

Very infrequently, paradoxical reactions may occur, for example, excitement, stimulation, hallucinations, hyperactivity and insomnia.

A few patients will experience a paradoxical reaction to benzodiazepines, and their anxiety will get worse.

One is that some children may have a "paradoxical" reaction to the drugs that causes them to become extremely restless, agitated or impulsive.