The reaction mechanism usually begins with oxidative addition of one organic halide to the catalyst.

Generally, these retardants are organic halides (haloalkanes) such as Halon and PhostrEx.

Vinyl fluoride is an organic halide with the chemical formula CHF.

The Stille reaction couples organotin compounds with organic halides or pseudohalides.

These methods weaken the passivating layer of MgO, thereby exposing highly reactive magnesium to the organic halide.

Halide displacement, using the suitable organic halide and sodium hydrogen sulfide has also been utilized.

They expose the magnesium to the organic halide to start the reaction that makes the Grignard reagent.

Bromotrifluoromethane is an organic halide with the chemical formula CBrF.

Allyl bromide (1-bromoprop-2-ene) is an organic halide.

This reactivity, when combined with a palladium salt, creates a carbon-carbon bond with an electrophillic carbon, like an organic halide.