Other organ involvement may occur later in the course of the disease.

In the subacute form, affected individuals may experience no symptoms (asymptomatic), even with organ involvement.

Symptoms associated with other organ involvement may follow.

In these cases, the generalized lymphadenopathy is frequently associated with visceral organ involvement.

Gleeson is the only other author to have documented this pattern of organ involvement.

The disease involves isolated patches of hardened skin - there generally is no internal organ involvement.

It's simple, and you may well be reducing the risk of organ involvement.

Patients may or may not experience systemic organ involvement.

Those with very widespread skin and organ involvement (systemic) have a negative prognosis.

The most common site of internal organ involvement is the liver.