The optimal dose, schedule, and route of administration, however, have not been established.

The optimal dose of postoperative thoracic radiation therapy is not known at this time.

However, they need to be confirmed, and the optimal dose, timing, and duration of use needs to be worked out, he says.

The optimal dose of radiation therapy has not been determined.

Today, Sam takes his optimal - and much lower - dose.

The optimal dose for this purpose has not been established.

Pharmacokinetic data are important for determining the optimal dose or schedule of a drug.

The best drug, the optimal dose and duration of therapy for a particular patient are not determined directly by a study involving a large population.

The optimal pediatric dose of voriconazole is not yet known.

That technique also has practical applications, such as determining the optimal dose of a medicine.