The opening of the university caused intense public debate.

This allows an opening for bacteria to enter around the tooth and cause an infection.

The opening of the mines at the end of the 19th century caused significant changes in the character and life of the village.

The openings did not cause the fire to spread.

In 1991, the opening of an art exhibition caused a huge turn out of the police.

The opening of the sluice-gates had directly caused the deaths of more than 400 people.

Remember that the opening and closing of doors nearby can cause problems for pampered plants, particularly early leaf drop.

What is it whose closing causes the dark and whose opening causes the light?

The sun streamed in, and the tiny openings of the windows caused the passengers to broil.

So the forced opening of any one of them could perhaps cause irreparable harm to the living contents.