You see, it's short on mutations; it does not enjoy Earth's high level of natural radiation.
The other mode depends on occasional small mutations, like the changes in the parameters of protozoa.
The proposal says researchers should focus on mutations that occur in at least 5 percent of tumors of a certain type.
The problem with these studies have been that they rely heavily on mutations in the coding region.
Like the chimpanzee, changes were on the level of gene rearrangements rather than single mutations.
Natural selection acting on random mutations will then result in hill-climbing up this higher peak.
A staging system for established cancer might also be based on genetic mutations.
Muller's work was increasingly focused on mutation rate and lethal mutations.
The evidence is very strong that such changes are indeed brought about by natural selection acting on random mutations.
Huskins worked at first on mutations in oats and wheat.