The show was hosted by a stationary picture of the Barker Bill character with an off-camera announcer introducing the cartoons.

An off-camera announcer said: "The one garment you should never shed is a condom."

Wally Wingert has served as the off-camera announcer since the start of Leno's second Tonight tenure, carrying over his duties from The Jay Leno Show.

On the first show, an off-camera announcer promised "comedy, clarity, catharsis."

An off-camera announcer clarified that "the views and opinions expressed on this broadcast do not necessarily reflect the views of the International Cable News Network or its subscribing stations."

Bob DeBardelaben - former off-camera announcer and weather anchor (1963-1989)

Bob Vernon - noon anchor and off-camera announcer (1989-1995) (deceased)

The show is produced by British-Australian former talk show host Gordon Elliott, who also serves as the show's off-camera announcer.

In the beginning, the show ran 90 minutes long, and consisted of music videos introduced by an off-camera announcer.

Nick Michaels and Scott Muni were the off-camera announcers.