In two strains of obese mice, the ob gene was found to be defective, suggesting that when it malfunctions, it causes obesity.

KLF15 in adipose tissue is down-regulated in obese mice.

Moreover, both obese and normal mice quickly lost body fat when given injections of leptin made by genetic engineering.

Research has shown that obese mice and humans have low circulating PYY concentrations.

Ob-X reduces body weight gain and visceral adipose tissue mass in genetically obese mice.

Another study found Mups were reduced in diet-induced obese mice.

A strain of monumentally obese mice turned out to lack the hormone.

Dr. Coleman was studying a strain of genetically obese mice that weighed three times as much as normal mice.

Evidence of anti-obesity effects of the pomegranate leaf extract in high-fat diet induced obese mice.

Indeed adrenalectomy initially led to a greater loss of body weight after surgery in the diet-induced obese mice (results in text above).