The high number of errors caused his intelligence to be called into question.

A number of factors can cause a drug to be recalled.

A number of different things can cause this to happen.

A number of factors are causing that to happen faster than anyone expected.

A large number of toxic plants may also cause symptoms.

"That number is pretty ugly, and could cause some problems for the Treasury market."

In fact, large numbers of these new species aren't causing a problem.

However, the massive number of tourists also causes many problems.

Such large numbers of visitors in a tiny town has caused problems.

The large number of prisoners, however, caused them some trouble.