Figure 1 shows the strong nuclear staining seen in one of these adenomas.
But, they did not report a great variability in theintensity of nuclear staining.
In both cases, the intensity of nuclear staining was variable.
These differences included changes in central epithelial nuclear staining, nuclear shape and epithelial thickness and continuity.
The most prominent nuclear staining was found in trophoblast cells merging with the syncytium (full arrowheads vs. white).
However, we interpreted this as being the result of cytoplasmic staining overlying the nucleus, rather than nuclear staining.
When the hydrogen peroxide volume reached 300 l, both cytoplasmic and nuclear staining were virtually abolished.
We evaluated the intensity of nuclear staining in 34 cases of paraffin-embedded tissues.
The mechanism is different from that of nuclear staining by basic (cationic) dyes such as thionine or toluidine blue.
It is especially good for gastrointestinal tract biopsies because this fixative allows crisper and better nuclear staining than 10% neutral-buffered formalin.