"Is there any history of nasty diseases in your family?"

You seem surprised that this is a really nasty disease.

And why did this nasty disease wander so far north?

Strangles is a nasty disease that is still seen too frequently.

This Age had a number of nasty diseases.

Believe me, Marty, this is a bad decade to be a bachelor, so many really nasty diseases out there.

Lordy, cats carried all sorts of nasty diseases, didn't they?

I think that aside from some sure-enough nasty disease, most c health is in your head anyway.

And no bacteria known to cause nasty diseases through casual contact.