It replicates in the nasal and nasopharyngeal tissues and the tonsils.

The nasal formulation acts directly on the blood vessels in the nasal tissues.

Longer use could cause damage to the nasal tissue and lead to chronic congestion.

This often results in considerable irritation, discomfort, burning, or itching of the affected nasal tissue and nostrils.

There is alcohol involved as well, and probably cocaine, to judge from the nasal tissues.

However, as no fossilised nasal tissue has been found, this remains conjectural.

Rapid absorption through nasal tissues makes snorting cocaine nearly as fast-acting.

Seeds, such as beans or popcorn, can swell from the moistness of the nasal tissue, making removal more difficult.

The nasal tissue can be damaged from pressure against the object.