Moreover, with strictly asexual reproduction, mutations will inevitably accumulate.
During a neutralist regime, neutral mutations accumulate, and so genetic diversity increases.
Neutral mutations can accumulate over time due to genetic drift or genetic draft.
These mutations can accumulate and may allow cells to grow and divide uncontrollably to form a tumor.
The mutations accumulated in both paralogs would have been deleterious if they had not been complimented by the other copy.
At its foundation, this technology allows researchers to observe the frequency with which mutations accumulate in single cells.
Nonlethal mutations accumulate within the gene pool and increase the amount of genetic variation.
Therefore, late-acting deleterious mutations could accumulate in populations over evolutionary time through genetic drift.
When enough mutations accumulate, a cell becomes malignant and a tumor begins to grow.
Other viruses change more slowly as mutations in their genes gradually accumulate over time, a process known as genetic drift.