A clinical trial shows that breast-fed infants with colic who are given a specific multi-ingredient product containing fennel, lemon balm, and German chamomile (Colimil) cry for a shorter period of time than other infants with colic.

For colic in breast-fed infants: a specific multi-ingredient product containing 164 mg of fennel, 97 mg of lemon balm, and 178 mg of German chamomile (Colimil) twice daily for a week.

Relieving symptoms of a psychiatric disorder known as "adjustment disorder with anxious mood" when used in a multi-ingredient product (Euphytose, EUP).

Manganese is sometimes included with chondroitin sulfate and glucosamine hydrochloride in multi-ingredient products promoted for osteoarthritis.

Research also shows that a specific multi-ingredient commercial product (Enzyte, Berkeley Premium Nutraceuticals) that contains horny goat weed might cause abnormal heart beats when measured by an electrocardiogram.

For colic: A specific multi-ingredient product containing 164 mg of fennel, 97 mg of lemon balm, and 178 mg of German chamomile (ColiMil, Milte Italia SPA) twice daily for a week.