Two mice will produce 2,500 offspring in a year.
The mouse grows without an immune system and produces offspring with similar deficiencies.
Breeding the mice produced subsequent generations that contained the human DNA in every cell, they said.
Twelve mice even mated and produced offspring, which showed no physical deficiencies.
Some rats and mice are producing fewer litters that are smaller than average.
American Biogenetic says the special diet helps its mice produce unusually selective and active antibodies when they receive foreign protein injections.
In the cluttered study the old mouse produced a yellowed volume.
Although the genetically altered mice produced about 50 times the normal amount of the protein in their muscles, they suffered no ill effects, the researchers said.
The mice produced seven pups, although one died and the other six had health problems.
The mice lacking the Lmx-1 produced ventral skin on both sides of their paws.