The development of the mouse embryo is the best experimental model for human development.
A quite different way of creating a chimaera is to fuse two early mouse embryos.
Although originally derived from a mouse embryo, the 3T3 cell line was developed in 1962.
Two hundred copies of the gene were injected into fresh mouse embryos.
As the mouse embryo developed, its cells divided over and over.
Dr. Efstratiadis wanted to know whether it also played a role in the development of mouse embryos.
There are many potential uses for this method of generating transgenic mouse embryos.
The cells in which it occurred could be isolated and transplanted into mouse embryos.
In mouse embryo, blastocoel formation begins at the 32-cell stage.
This occurs at E9.5 in the developing mouse embryo.