They have forced upon us the most grievous of measures, whereby the poor starve and the wealthy are impoverished.

A Midrash taught that the frogs were the most grievous of the ten plagues.

Her wide eyes were fixed on her father's changed, aged face, in the most grievous and desperate stare.

Both are wrong and their error is most grievous.

You have become resistant to most diseases and can recover from everything but the most grievous of wounds.

God is seen as being "He Who forgiveth even the most grievous of sins".

High school students argued vigorously for the resolution, describing books by dead white men as a most grievous hardship.

You claimed that was my most grievous sin.

The daughter of the house, at first a prey to the most grievous anxiety, had great difficulty in concealing her joy.

It's a crime of the most grievous kind.