Perhaps the most disconcerting thing for the newcomer is how to find your way around.
She turned her eyes on me in a most disconcerting fashion.
I believe that they found my resistance to be most disconcerting.
"Well, if you have, it is a most disconcerting one."
I found it most disconcerting to feel so helpless while surrounded by the enemy.
The old man was staring at her in a most disconcerting way.
In the most disconcerting way possible, he looked instantly dead.
The most disconcerting thing was that it felt right.
That was the most disconcerting feeling of my life.
In the 1920s, the most disconcerting economic issue was declining farm profits.