It has also been demonstrated that pre-dose metabolic profiles from urine can be used to predict drug metabolism.
Your metabolic profile shows that since the death of General Borzov you have only had a total of eleven hours of solid rest.
However, it was only through technological advancements in the 1960s and 1970s that it became feasible to quantitatively (as opposed to qualitatively) measure metabolic profiles.
Routine complete blood count (CBC), basic metabolic profile, liver enzymes, and coagulation should be performed.
Pharmacometabolomic analyses, through the use of a metabolomics approach, can provide a comprehensive and detailed metabolic profile or "metabolic fingerprint" for an individual patient.
Such metabolic profiles can provide a complete overview of individual metabolite or pathway alterations, providing a more realistic depiction of disease phenotype.
This approach can then be applied to the prediction of response to a pharmaceutical compound by patients with a particular metabolic profile.
The analysis revealed a certain metabolic profile associated with increased liver damage following paracetamol treatment.
This involves determining the metabolic profile of a patient prior to treatment, and correlating metabolic signatures with the outcome of a pharmaceutical treatment course.
The second major application of pharmacometabolomics is the analysis of a patient's metabolic profile following the administration of a specific therapy.