The diversity of life on Earth is a result of the dynamic interplay between genetic opportunity, metabolic capability, environmental challenges, and symbiosis.
However, when additional metabolic capabilities are discovered [ 42], the E. coli stoichiometric matrix can be updated, leading to an iterative model building process.
"It is important," Dr. Gordon said, "to think of our bodies as a summation of the metabolic capabilities provided by our own genome and the microbiome."
If the indigenous variety do not have the metabolic capability to perform the remediation process, exogenous varieties with such sophisticated pathways are introduced.
Termites achieve this high degree of efficiency by exploiting the metabolic capabilities of about 200 different species of microbes that inhabit their hindguts.
These findings provide evidence that antibiotics pertub not only the composition of GI microbiome but also its metabolic capabilities, specically with respect to SCFAs.
In filling this niche, FBA has been shown to be a very useful technique for analysis of the metabolic capabilities of cellular systems.
There are different types of myofibers, which vary in size and with respect to metabolic and contractile capability [16] (Figure 1).
Together, these partners create "animals" with novel metabolic capabilities.
Similar reduced metabolic capabilities are seen in endosymbiotic organisms.