Almost all ions and molecules require special membrane transporters to enter or exit the matrix.
In ALD the gene for this peroximal membrane transporter, ALDP, is defective, preventing long chain fatty acids from entering the peroxisome.
Such sites are located on active membrane transporters, Microtubule subunits, flagellum proteins, and various hydrolytic and proteolytic enzymes.
There are several different monoamine transporters each belonging to the family of Na /Cl -dependent substrate-specific neuronal membrane transporters.
However, the ABCG or White subfamily with its five fully characterized human members consists of half-size ABC proteins which probably dimerize to form active membrane transporters.
In yeast, there was an emphasis on membrane transporters as well as on genes involved in stress response (for example, heat shock).
These domains are usually enzymatic, membrane transporters or DNA-binding domains.
Role of high-affinity receptors and membrane transporters in nonsynaptic communication and drug action in the nervous system (co-author, 2000)
Transporter reversal is the action of reversing a membrane transporter via a process known as phosphorylation.
Recently, loss-of-function mutations in another putative membrane transporter, Indy , have been found to increase life span [ 15].