"If you got the job would it mean giving up general practice?"

But it doesn't have to mean giving up all good things.

Now he was going to have Rose, but it meant giving up just about everything else, including and especially his way of life.

Even if it meant giving up his own chance at life and freedom.

The down side would mean giving up on the mission.

At the most it may mean giving up a job.

A hard decision means giving up one thing to get another.

Eating well does not mean giving up all the things you like.

Didn't marriage mean giving up part of yourself to someone else?

But to face that would mean giving up all hope.