The establishment of the Ottoman rule caused a massive depopulation of the Vojvodina region.

During the early Qing Dynasty, a massive depopulation in Gannan due to the ravage of pestilence and war.

Teruel Province has undergone massive depopulation since the second half of the 20th century.

The Ottoman Empire took control of Vojvodina in the 16th century, and this caused a massive depopulation of the region.

After colonists left Earth, a plague caused massive depopulation on Earth.

The closure of the slate mines during the late 1970s led to massive depopulation of the area from which it has only recently (2005) begun to recover.

Christopher Columbus and the conquistadors, through their travels, were indirectly responsible for the massive depopulation of South America.

Foreign visitors were appalled by the evidence of massive depopulation, by the sight of whole villages abandoned.

In the nineteenth century a massive depopulation took place and the languages were realigned.

Since the 1950s, Smoketown has suffered from massive depopulation.