He said that such deep reductions would have a marked impact on the city's services and its workers.

Pythagorean philosophy had a marked impact on the thoughts of early modern scholars involved within the Scientific Revolution.

Turovsky also had a marked impact as a music educator.

The reverse had a marked impact on Moltke, whose mental concentration was at that time directed to the western theatre.

The painful nature of these adverse effects has a marked negative impact on patient compliance.

The decisions of their buyers can have a marked impact on the nation's gardens.

Lobbyists at other firms, though, said the new rules had not had a marked impact.

As a fund grows it becomes harder to own enough of a small company's stock to make a marked impact on the portfolio's performance.

The subject is clearly very important, both for its marked impact on health protection and for the fight against the criminal activities associated with the drug market.

Minimalism and pop art had a marked impact.