Drugs have a marked effect on the body and mind.

This development had a marked effect on the structure and nature of the fishing industry.

The power of the word seemed to have a marked effect.

It is now that the marked effect of training can most clearly be felt.

They all put rum into their coffee, which had a marked effect.

It will have a marked effect upon the values of the various stocks concerned.

It is expected to have a marked effect on the local economy by providing more jobs.

This can have a marked effect on any investment decision.

Most are able to do this without any marked ill effects.

But it will not have a marked effect on your life span, according to a study of more than 300,000 adults.