It is based in part on the TeX typesetting system, and uses a document markup language for manuscript preparation.

All authors contributed the manuscript preparation and approved the final paper.

CK participated in the study coordination and manuscript preparation.

GPB performed the analysis and participated in manuscript preparation.

KBM conceived of the study and participated in its design and manuscript preparation.

SR helped design, supervise and interpret studies and with manuscript preparation.

The basic rule of manuscript preparation is, Make the reading as easy as possible.

MJS participated in study design, coordination and manuscript preparation.

RDJ participated in the design of the study, analysis of the data and manuscript preparation.

RJM participated in study design, statistical analysis and manuscript preparation.