If manipulation leads to more pain, new pain, or numbness in the legs or anywhere else, stop the treatment.

In most men, such a manipulation would have led to obvious problems like breast growth, headaches, weight gain and mood alterations.

Excessive manipulation can sometimes lead to pain, as can simple things such as insect bites or pimples.

They became uncaring when they saw manipulation and politics, rather than hard work, lead to promotions.

How far is it inevitable that the manipulation of fact for the purposes of fiction leads to romanticising?

This manipulation of the judicial system often led judges to severely restrict union picketing near company property.

He is also presented as cynical - believing that manipulation, far more than the quality of scholarship, leads to promotion.

As a result, the biologists' many manipulations led them backward in time to their sub-Saharan Eve, "the world's one common grandmother."

His manipulation of the democratic processes and institutions that were put in place have led some analysts to condemn the United Nations effort as a failure.

And such manipulation will inevitably lead to collapse and destruction.