Does getting the disease have something to do with the timing of puberty and breast development, something that sets up a risk in the mammary tissue?
SCGB2A1 expression is highly specific of mammary tissue, and has been used for identification and detection of disseminated breast cancer cells.
This may then affect the developing mammary tissue such that the lifetime risk of breast cancer is raised in their daughters.
One question that inevitably comes up is whether there is something peculiar about the way sheep mammary tissues differentiate.
Older mice are susceptible to tumors, especially breast cancer in females as the mammary tissue is distributed around much of the body.
These tissues include the thyroid, adrenal gland, pancrease, and mammary tissues .
Its role in mammary tissue is related to fetal and neonatal development, but its role in the other tissues is unknown.
The achievement indicated that the transplanted gene became activated in the proper way and in the proper place: the mammary tissues involved in milk production.
SCGB1D2 expression is high in mammary tissue, and is sometimes used for identification and detection of disseminated breast cancer cells.
In tissue cultures insulin is an absolute requirement for the growth proliferation of normal mammary tissue and breast cancer cells are, at least initially, also dependent on it.