Isotretinoin's main indication is for the treatment of severe cystic acne vulgaris.

The main indications for positive airway pressure are congestive heart failure and chronic obstructive pulmonary disease.

The visual examination of the taken liquid is a first main indication for the pathologist or the physician.

The main indications for dynamic smile reconstruction are unilateral or bilateral facial paralysis due to acquired and congenital causes.

The main indication is denervation of the pelvic floor (e.g. descending perineum syndrome).

Often the first remedy needed because of the shock, which is the main indication.

The respiratory symptoms are its main indication for use.

The main indication of a problem that can be seen in an animation is the forming of persistent queues.

The main indication that the settlement was a Jewish one is the assemblage of stone vessels found there.

Interestingly, there was a tendency that the main indications for sedation during the last three years shifted more and more to psychological distress.