Patients are considered to have either localized or metastatic disease.

Patients with localized disease may be classified into three groups:

Patients diagnosed with localized disease require less treatment and have lower morbidity.

Thus, antibiotic treatment usually is not recommended for uncomplicated localized disease.

The available data did not allow us to restrict our analyses to cases with just localized disease.

Five-year survival for localized disease is 70% to 80% when treated with chemotherapy.

The site of the primary tumor is a significant prognostic factor for patients with localized disease.

The exception is localized disease, which can be cured by local irradiation.

OS in patients with localized disease did not seem related to tumor site or size.

"We're trying to build up pressure so people realize it's not just a localized disease," he said.