The settlement was largely depopulated by the late 1680s.

However, both the vegetation and the fauna are largely depopulated because of strong human population pressure.

By the end of antiquity, the city was largely depopulated, hosting only a small Christian community.

Many German towns and churches were destroyed and the region was largely depopulated.

However, the area was largely depopulated by the smallpox plague that swept across the Americas after the arrival of Europeans.

Within two years the southern Bahamas were largely depopulated.

In the 1920s and 1930s it was largely depopulated during the Dust Bowl, although some buildings still remain.

The villages were largely depopulated and after the war virtually had to be repopulated.

Although the area was largely depopulated after 1977, several positive developments took place.

With the establishment of the initial British settlement, these are suspected to have been largely depopulated by disease shortly after 1789.