A spray of large and painful pimples recently sprouted there.

A boil (abscess), similar to a large pimple.

Cystic lesions from acne are large pimples that occur deep under the skin.

Draining of large pimples and cysts by a doctor.

A large, florid pimple blossomed from one hollow cheek.

Cystic lesions from acne, sometimes called acne cysts, are large and painful pimples deep under a person's skin that develop most often on the face, neck, or upper body.

Plaques can be thought of as large "pimples" that protrude into the channel of an artery, causing a partial obstruction to blood flow.

To wit, a large pimple gleamed insolently from his cheek, resisting the king's most arduous attempts to remove it.

But the classic symptom is the formation of large pimples under the upper lid.

Acne may be mild, with just a few blackheads (comedones), or severe, with large and painful pimples deep under the skin (cystic lesions).