The century old building was not only lost but it also had a large effect to the other buildings in the area.
Access to appropriate treatment has a large effect on outcome.
How they are assembled has a large effect on mass.
That is why a small error had such a large effect.
The effects, large and small, are already being felt across the city.
Small differences in behavior can have large effects on learning and big implications for class size.
Show how an increase in money supply will have a larger effect on national income.
I just don't think it will have such a large effect.
He said a surge in oil prices would probably not by itself have a large effect on the American economy.
Planning does make a difference, identifying where a little money might have a large effect.