He had given up everything in its cause, his life irrevocably changed.
Why did he feel as though his life had just changed irrevocably?
But the world had irrevocably changed in those three days.
Of course, it could not last, but the experience had left him irrevocably changed.
Already, they both knew that their lives had been irrevocably changed.
In the year following the 9/11 attacks, the world changed irrevocably.
The power of his language has irrevocably changed us and our poetry.
But her life, like everything else about the neighborhood, is irrevocably changing.
From the moment of diagnosis, their lives are irrevocably changed.
After Sept. 11 it was said by many that our world had irrevocably changed.